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Caraphenol A May Facilitate Faster, More Effective Gene Therapies for Sickle Cell Anemia, Study Says

BY PATRICIA INACIO, PHD IN NEWS. Caraphenol A — a small molecule closely related to a natural compound called resveratrol, which is produced by red grapes — increased the efficacy of hematopoietic stem cell-based gene therapy, a new study shows. The molecule holds potential to shorten the time and cost of using these...

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NIH launches new collaboration to develop gene-based cures for sickle cell disease and HIV on global scale

Initial investment aims to advance accessible and scalable candidate interventions into clinical trials within 10 years. The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease (SCD) and HIV. The Bill...

Transcranial Doppler Ultrasound Screening 4

Transcranial Doppler Ultrasound Screening

Sarah Neidler Transcranial Doppler ultrasound screening (TCD) is a test that uses ultrasound to measure the velocity or speed of blood flow through the blood vessels in the brain. It serves as a predictor for the risk of stroke. Sickle cell anemia and risk of stroke Sickle cell anemia patients carry a mutation...

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Tips for Traveling by Airplane with Sickle Cell

OCTOBER 23, 2019 BY TITO OYE IN COLUMNS, HER SICKLED JOURNEY – A COLUMN BY TITO OYE. In my previous column, I shared my suggestions on the preparations you should consider before taking a trip with sickle cell. The environment inside an airplane is not ideal for our bodies. On a flight, we are subjected...

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Voxelotor May Reduce Severity and Number of Leg Ulcers, Trial Analysis Suggests

BY MARISA WEXLER, MS IN NEWS. Voxelotor can reduce the severity of existing leg ulcers and the incidence of new ones in people with sickle cell disease (SCD), new clinical trial results suggest. The findings detailed by the treatment’s developer, Global Blood Therapeutics (GBT), are being presented at the 13th Annual Academy for Sickle Cell and Thalassemia Conference,...

Sickle Cell Anemia and Fatigue 0

Sickle Cell Anemia and Fatigue

Sickle cell anemia is a heritable disease caused by a mutation in the gene that provides instructions for the production of hemoglobin, the protein in red blood cells that carries oxygen. This mutation causes the red blood cells to become deformed and adopt an inflexible “sickle” shape that has difficulty traveling through small...

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KYGC AT AGBARHO

The free Genotype test campaign was carried out in Agbarho town in Delta State, participation was a 100 persons. The aim of this test is to educate people on the importance of knowing their genotype in other to avoid Sickle Cell births, ASCF also enlightened the participants about the disorder...

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VASO OCCLUSIVE CRISIS

Sickle cell anemia is an inherited disorder that is caused by a mutation in the gene encoding for hemoglobin, which is the protein in red blood cells that carries oxygen. The altered form of hemoglobin in patients with this condition is called hemoglobin S or sickle hemoglobin. Sickle cell anemia patients often experience episodes of...