The Life of a Sickle Cell Warrior.
In 1910, James Herrick first described sickle cell disease (SCD). SCD is a disorder that affects the molecule called haemoglobin found in red blood cells whose function is to deliver oxygen to the cells in the body. SCD is caused by a mutation of this haemoglobin molecules which forms polymers...
BY PATRICIA INACIO, PHD IN NEWS. The National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation will each invest $100 million over the next four years to speed the development of affordable gene therapies for sickle cell disease (SCD) and the human immunodeficiency virus (HIV) on a global scale. “This unprecedented collaboration focuses from the get-go on...
BY ALANA KESSLER IN NEWS. Strong evidence points to some complications of sickle cell anemia (SCA) having as much to do with nutrition as they do with genes. Characteristics and symptoms of the disease include poor growth, pain, infection, decreased muscle function, problems with cognition and coordination, low antioxidant status, and anemia. Hypermetabolism —...
BY PATRICIA INACIO, PHD IN NEWS. Caraphenol A — a small molecule closely related to a natural compound called resveratrol, which is produced by red grapes — increased the efficacy of hematopoietic stem cell-based gene therapy, a new study shows. The molecule holds potential to shorten the time and cost of using these...
Initial investment aims to advance accessible and scalable candidate interventions into clinical trials within 10 years. The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease (SCD) and HIV. The Bill...
Sarah Neidler Transcranial Doppler ultrasound screening (TCD) is a test that uses ultrasound to measure the velocity or speed of blood flow through the blood vessels in the brain. It serves as a predictor for the risk of stroke. Sickle cell anemia and risk of stroke Sickle cell anemia patients carry a mutation...
OCTOBER 23, 2019 BY TITO OYE IN COLUMNS, HER SICKLED JOURNEY – A COLUMN BY TITO OYE. In my previous column, I shared my suggestions on the preparations you should consider before taking a trip with sickle cell. The environment inside an airplane is not ideal for our bodies. On a flight, we are subjected...
BY TITO OYE IN COLUMNS, HER SICKLED JOURNEY – A COLUMN BY TITO OYE. Ed. note: Welcome to the new column, “Her Sickled Journey,” by Tito Oye. Living with sickle cell anemia means that you have unknowingly agreed to a lifelong role of teaching. Many others are unaware of the challenges faced by those with...
BY MARISA WEXLER, MS IN NEWS. Voxelotor can reduce the severity of existing leg ulcers and the incidence of new ones in people with sickle cell disease (SCD), new clinical trial results suggest. The findings detailed by the treatment’s developer, Global Blood Therapeutics (GBT), are being presented at the 13th Annual Academy for Sickle Cell and Thalassemia Conference,...
The free Genotype test campaign was carried out in Agbarho town in Delta State, participation was a 100 persons. The aim of this test is to educate people on the importance of knowing their genotype in other to avoid Sickle Cell births, ASCF also enlightened the participants about the disorder...
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